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TargetCholinergic receptors

Nicotinic acetylcholine receptor alpha 5 subunit

Muscarinic and nicotinic acetylcholine receptors.

Measurements
2
Compounds
2
Binding constants
2
Median pX
4.49

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

Nicotinic acetylcholine receptor alpha 5 subunit has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.

Resolver said gene not found in the Human Protein Atlas — recorded by tools/fetch_expression.py, not written here.

III · Ranking

Compounds by strongest binding constant

One bar per compound: its strongest Ki or Kd at this target, expressed as pX. Compounds measured here only by a functional assay do not appear — they are in the table below.

  1. 01Atropine4.49

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Equilibrium binding constants 2

Ki and Kd — a concentration at equilibrium. Directly comparable across rows at the same target.

TargetClassTypeValue (nM)pXOrganismAssay
Nicotinic acetylcholine receptor alpha 5 subunitCholinergic receptorsKi32,5004.49Musca domesticaCHEMBL3075135
Nicotinic acetylcholine receptor alpha 5 subunitCholinergic receptorsKi— no normalized value— value does not convert to pXMusca domesticaCHEMBL3075135
Nicotinic acetylcholine receptor alpha 5 subunit · Psychedelia