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TargetEnzymes

Thioredoxin glutathione reductase

Named enzymes, including the metabolising cytochromes and the monoamine oxidases.

Measurements
5
Compounds
5
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

Thioredoxin glutathione reductase has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.

Resolver said gene not found in the Human Protein Atlas — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 5

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
Thioredoxin glutathione reductaseEnzymesPotency— no normalized value— value does not convert to pXSchistosoma mansoniCHEMBL1614161
Thioredoxin glutathione reductaseEnzymesPotency— no normalized value— value does not convert to pXSchistosoma mansoniCHEMBL1614161
Thioredoxin glutathione reductaseEnzymesPotency— no normalized value— value does not convert to pXSchistosoma mansoniCHEMBL1614161
Thioredoxin glutathione reductaseEnzymesPotency— no normalized value— value does not convert to pXSchistosoma mansoniCHEMBL1614161
Thioredoxin glutathione reductaseEnzymesPotency— no normalized value— value does not convert to pXSchistosoma mansoniCHEMBL1614161
Thioredoxin glutathione reductase · Psychedelia