Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
5-HT receptor subtypes.
- Measurements
- 3
- Compounds
- 3
- Binding constants
- 1
- Median pX
- 7.13
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.
III · Ranking
Compounds by strongest binding constant
One bar per compound: its strongest Ki or Kd at this target, expressed as pX. Compounds measured here only by a functional assay do not appear — they are in the table below.
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Equilibrium binding constants 1
Ki and Kd — a concentration at equilibrium. Directly comparable across rows at the same target.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Serotonin receptor 2a and 2c (5HT2A and 5HT2C) | Serotonin receptors | Ki | 74.50 | 7.13 | Rattus norvegicus | CHEMBL617366 |
Other measurements 2
Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Serotonin receptor 2a and 2c (5HT2A and 5HT2C) | Serotonin receptors | Ratio | — no normalized value | — value does not convert to pX | Rattus norvegicus | CHEMBL826017 |
| Serotonin receptor 2a and 2c (5HT2A and 5HT2C) | Serotonin receptors | nH | — no normalized value | — value does not convert to pX | Rattus norvegicus | CHEMBL617026 |