Serotonin 2 receptors; 5-HT2a & 5-HT2c
5-HT receptor subtypes.
- Measurements
- 21
- Compounds
- 10
- Binding constants
- 1
- Median pX
- —
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
Serotonin 2 receptors; 5-HT2a & 5-HT2c has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Equilibrium binding constants 1
Ki and Kd — a concentration at equilibrium. Directly comparable across rows at the same target.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4372844 |
Other measurements 20
Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Selectivity ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4258726 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Selectivity ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL847870 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Selectivity ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL847870 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Selectivity | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL849570 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio IC50/EC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL5509711 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Selectivity ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL927578 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Selectivity ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL927578 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Selectivity ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL927578 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL921964 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL921964 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio EC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL921971 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio EC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL921971 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL5142994 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio EC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL957596 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL2446186 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4309133 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4617402 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL3756324 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Selectivity ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL3590939 |
| Serotonin 2 receptors; 5-HT2a & 5-HT2c | Serotonin receptors | Ratio Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL936732 |