Serine/threonine-protein kinase 17B
Named enzymes, including the metabolising cytochromes and the monoamine oxidases.
- Measurements
- 1
- Compounds
- 1
- Binding constants
- 0
- Median pX
- —
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
Serine/threonine-protein kinase 17B
Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis
Quoted from UniProt’s FUNCTION annotation for O94768 (reviewed).
What it acts with
STRING’s highest-confidence human functional partners. The combined score mixes several kinds of evidence, so each channel is shown separately — a partner supported by experiment is a different claim from one supported only by text mining, and for a receptor this is where its coupling appears as evidence rather than as assertion.
Where it sits in the cell
- Nucleoplasm
Human Protein Atlas, by antibody immunofluorescence in cell lines — a different assay from the expression figures below, which are RNA.
UniProt, curated Nucleus · Cell membrane · Endoplasmic reticulum-Golgi intermediate compartment
Expression by cell type
Single cell type RNA, the 12 highest of those the Human Protein Atlas reports for this gene. Transcript, not protein, and a cell type rather than a tissue.
- Neutrophils3,217 nCPM
- Neutrophil progenitors1,111.7 nCPM
- T-cells869.4 nCPM
- Mast cells789.8 nCPM
- monocytes783.8 nCPM
- cDC761.5 nCPM
- Thymocytes653.8 nCPM
- Innate lymphoid cells639.1 nCPM
- B-cells616.6 nCPM
- NK-cells616.6 nCPM
- Monocyte progenitors581.2 nCPM
- Hematopoietic stem cells525 nCPM
Expression by tissue
The tissues this gene is enriched in, by consensus RNA. A tissue absent from this list is one the Atlas does not call specific for this gene, which is not the same as absent from it.
- bone marrow355.5 nTPM
- lymphoid tissue105.8 nTPM
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Other measurements 1
Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase 17B | Enzymes | Activity | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4151460 |