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TargetOther named receptors

Olfactory receptor 5K1

A named receptor outside the families above. The catch-all is explicit rather than silent: these are receptors, but they are not grouped.

Measurements
1
Compounds
1
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

Protein

OR5K1_HUMANOR5K1Homo sapiens

Olfactory receptor 5K1

Odorant receptor

Quoted from UniProt’s FUNCTION annotation for Q8NHB7 (reviewed).

What it acts with

STRING’s highest-confidence human functional partners. The combined score mixes several kinds of evidence, so each channel is shown separately — a partner supported by experiment is a different claim from one supported only by text mining, and for a receptor this is where its coupling appears as evidence rather than as assertion.

PartnerCombinedExperimentDatabaseText mining
GNAL0.6860.1420.6500.000
GNB10.6820.1290.6500.000
ARRB10.6790.1080.6500.056
ARRB20.6790.1080.6500.056
GNG70.6780.1200.6500.000
GNG130.6780.1200.6500.000
GRK30.6700.0970.6500.042
GRK20.6700.0970.6500.042
PRKACA0.6500.0000.6500.042
PRKACB0.6500.0000.6500.042

Where it sits in the cell

UniProt, curated Cell membrane

Expression by cell type

Single cell type RNA, the 1 highest of those the Human Protein Atlas reports for this gene. Transcript, not protein, and a cell type rather than a tissue.

  • Cardiomyocytes9.8 nCPM

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Other measurements 1

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
Olfactory receptor 5K1Other named receptorsInhibition— no normalized value— value does not convert to pXHomo sapiensCHEMBL3734176