Muscarinic acetylcholine receptors; M1 & M2
Muscarinic and nicotinic acetylcholine receptors.
- Measurements
- 5
- Compounds
- 3
- Binding constants
- 1
- Median pX
- —
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
Muscarinic acetylcholine receptors; M1 & M2 has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Equilibrium binding constants 1
Ki and Kd — a concentration at equilibrium. Directly comparable across rows at the same target.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptors; M1 & M2 | Cholinergic receptors | Ki | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL743979 |
Other measurements 4
Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptors; M1 & M2 | Cholinergic receptors | M2/M1 index | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL848570 |
| Muscarinic acetylcholine receptors; M1 & M2 | Cholinergic receptors | Ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL846393 |
| Muscarinic acetylcholine receptors; M1 & M2 | Cholinergic receptors | Ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL849039 |
| Muscarinic acetylcholine receptors; M1 & M2 | Cholinergic receptors | K app ratio | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL849787 |