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TargetGlutamate receptors

Metabotropic glutamate receptor

NMDA, AMPA, kainate and metabotropic receptors.

Measurements
2
Compounds
2
Binding constants
2
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

No single gene answers to Metabotropic glutamate receptor. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.

Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Equilibrium binding constants 2

Ki and Kd — a concentration at equilibrium. Directly comparable across rows at the same target.

TargetClassTypeValue (nM)pXOrganismAssay
Metabotropic glutamate receptorGlutamate receptorsKi— no normalized value— value does not convert to pXRattus norvegicusCHEMBL711160
Metabotropic glutamate receptorGlutamate receptorsKi— no normalized value— value does not convert to pXRattus norvegicusCHEMBL711160