L-lactate dehydrogenase B chain
Named enzymes, including the metabolising cytochromes and the monoamine oxidases.
- Measurements
- 9
- Compounds
- 9
- Binding constants
- 0
- Median pX
- —
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
L-lactate dehydrogenase B chain
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)
Quoted from UniProt’s FUNCTION annotation for P07195 (reviewed).
Where it sits in the cell
- Cytosol
- Primary ciliumadditional
Human Protein Atlas, by antibody immunofluorescence in cell lines — a different assay from the expression figures below, which are RNA.
UniProt, curated Cytoplasm · Mitochondrion inner membrane
Expression by cell type
Single cell type RNA, the 1 highest of those the Human Protein Atlas reports for this gene. Transcript, not protein, and a cell type rather than a tissue.
- Parietal cells1,143.8 nCPM
Expression by tissue
The tissues this gene is enriched in, by consensus RNA. A tissue absent from this list is one the Atlas does not call specific for this gene, which is not the same as absent from it.
- heart muscle1,824.5 nTPM
- kidney1,610.4 nTPM
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Other measurements 9
Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| L-lactate dehydrogenase B chain | Enzymes | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4842433 |
| L-lactate dehydrogenase B chain | Enzymes | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4842433 |
| L-lactate dehydrogenase B chain | Enzymes | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4842433 |
| L-lactate dehydrogenase B chain | Enzymes | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4842433 |
| L-lactate dehydrogenase B chain | Enzymes | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4842433 |
| L-lactate dehydrogenase B chain | Enzymes | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4842433 |
| L-lactate dehydrogenase B chain | Enzymes | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4842433 |
| L-lactate dehydrogenase B chain | Enzymes | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4842433 |
| L-lactate dehydrogenase B chain | Enzymes | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4842433 |