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TargetOther named receptors

Glycine receptor

A named receptor outside the families above. The catch-all is explicit rather than silent: these are receptors, but they are not grouped.

Measurements
14
Compounds
7
Binding constants
7
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

No single gene answers to Glycine receptor. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.

Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Equilibrium binding constants 7

Ki and Kd — a concentration at equilibrium. Directly comparable across rows at the same target.

TargetClassTypeValue (nM)pXOrganismAssay
Glycine receptorOther named receptorsKi— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsKi— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsKi— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsKi— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsKi— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsKi— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsKi— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155

Functional readouts 7

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
Glycine receptorOther named receptorsIC50— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsIC50— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsIC50— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsIC50— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsIC50— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsIC50— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155
Glycine receptorOther named receptorsIC50— no normalized value— value does not convert to pXRattus norvegicusCHEMBL1909155