Cyclin-dependent kinase 5/CDK5 activator 1
Named enzymes, including the metabolising cytochromes and the monoamine oxidases.
- Measurements
- 7
- Compounds
- 1
- Binding constants
- 0
- Median pX
- —
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
No single gene answers to Cyclin-dependent kinase 5/CDK5 activator 1. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.
Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Functional readouts 7
IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Cyclin-dependent kinase 5/CDK5 activator 1 | Enzymes | IC50 | 8,000 | 5.10 | Homo sapiens | CHEMBL3381515 |
| Cyclin-dependent kinase 5/CDK5 activator 1 | Enzymes | IC50 | 8,000 | 5.10 | Homo sapiens | CHEMBL2182304 |
| Cyclin-dependent kinase 5/CDK5 activator 1 | Enzymes | IC50 | 20,000 | 4.70 | Homo sapiens | CHEMBL5242297 |
| Cyclin-dependent kinase 5/CDK5 activator 1 | Enzymes | IC50 | 21,000 | 4.68 | Homo sapiens | CHEMBL663604 |
| Cyclin-dependent kinase 5/CDK5 activator 1 | Enzymes | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL2320288 |
| Cyclin-dependent kinase 5/CDK5 activator 1 | Enzymes | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL3875854 |
| Cyclin-dependent kinase 5/CDK5 activator 1 | Enzymes | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL5251363 |