Adrenergic receptor alpha-1
α and β adrenoceptors.
- Measurements
- 3
- Compounds
- 3
- Binding constants
- 3
- Median pX
- 6.47
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
Adrenergic receptor alpha-1 has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.
III · Ranking
Compounds by strongest binding constant
One bar per compound: its strongest Ki or Kd at this target, expressed as pX. Compounds measured here only by a functional assay do not appear — they are in the table below.
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Equilibrium binding constants 3
Ki and Kd — a concentration at equilibrium. Directly comparable across rows at the same target.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Adrenergic receptor alpha-1 | Adrenergic receptors | Ki | 236 | 6.63 | Rattus norvegicus | CHEMBL651986 |
| Adrenergic receptor alpha-1 | Adrenergic receptors | Ki | 337 | 6.47 | Rattus norvegicus | CHEMBL651986 |
| Adrenergic receptor alpha-1 | Adrenergic receptors | Ki | 913 | 6.04 | Rattus norvegicus | CHEMBL651986 |