TargetCell lines

U-87 MG

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements: 10
Compounds: 5
Binding constants: 0
Median pX: —

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

U-87 MG has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 4

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

Target	Class	Type	Value (nM)	pX	Organism	Assay
U-87 MG	Cell lines	IC50	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL6109690
U-87 MG	Cell lines	IC50	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL6109691
U-87 MG	Cell lines	IC50	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL6118156
U-87 MG	Cell lines	IC50	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL6135105

Other measurements 6

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

Target	Class	Type	Value (nM)	pX	Organism	Assay
U-87 MG	Cell lines	ED50	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL815094
U-87 MG	Cell lines	ED50	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL815094
U-87 MG	Cell lines	Activity	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL6118157
U-87 MG	Cell lines	Inhibition	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL6118051
U-87 MG	Cell lines	Inhibition	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL6118051
U-87 MG	Cell lines	Inhibition	— no normalized value	— value does not convert to pX	Homo sapiens	CHEMBL6118051

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