TargetOrganisms

Trypanosoma cruzi

Whole-organism screens (antiparasitic, antibacterial, antiviral). Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements: 23
Compounds: 6
Binding constants: 0
Median pX: —

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

No single gene answers to Trypanosoma cruzi. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.

Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 9

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

Target	Class	Type	Value (nM)	pX	Organism	Assay
Trypanosoma cruzi	Organisms	IC50	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL1216998
Trypanosoma cruzi	Organisms	IC50	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL1216998
Trypanosoma cruzi	Organisms	IC50	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL1216998
Trypanosoma cruzi	Organisms	IC50	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL1216998
Trypanosoma cruzi	Organisms	IC50	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049471
Trypanosoma cruzi	Organisms	EC50	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049472
Trypanosoma cruzi	Organisms	IC50	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049473
Trypanosoma cruzi	Organisms	EC50	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL4700266
Trypanosoma cruzi	Organisms	EC50	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL4700267

Other measurements 14

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

Target	Class	Type	Value (nM)	pX	Organism	Assay
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049470
Trypanosoma cruzi	Organisms	FICI	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049478
Trypanosoma cruzi	Organisms	FICI	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049479
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049480
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049489
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049490
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049481
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049482
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049483
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049484
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049485
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049486
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049487
Trypanosoma cruzi	Organisms	Activity	— no normalized value	— value does not convert to pX	Trypanosoma cruzi	CHEMBL2049488

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