Skip to content
PsychedeliaDokholyan Laboratory
TargetCell lines

SH-SY5Y

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
30
Compounds
14
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

SH-SY5Y is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 18

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
SH-SY5YCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321398
SH-SY5YCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321398
SH-SY5YCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321398
SH-SY5YCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321398
SH-SY5YCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321398
SH-SY5YCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321398
SH-SY5YCell linesPotency— no normalized value— value does not convert to pXHomo sapiensCHEMBL1794380
SH-SY5YCell linesPotency— no normalized value— value does not convert to pXHomo sapiensCHEMBL1794380
SH-SY5YCell linesPotency— no normalized value— value does not convert to pXHomo sapiensCHEMBL1794380
SH-SY5YCell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1116560
SH-SY5YCell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1116560
SH-SY5YCell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1116560
SH-SY5YCell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1116560
SH-SY5YCell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1116560
SH-SY5YCell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1676755
SH-SY5YCell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1676755
SH-SY5YCell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1676755
SH-SY5YCell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169110

Other measurements 12

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321405
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321405
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321405
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321405
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321405
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321405
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5144383
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5144385
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5360496
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5360502
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5360513
SH-SY5YCell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5360517
← All targets