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TargetUnclassified

Sciatic nerve

Matched no rule. Shown as-is rather than assigned a class by guesswork. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
6
Compounds
1
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

Sciatic nerve has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 1

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
Sciatic nerveUnclassifiedIC50— no normalized value— value does not convert to pXRattus norvegicusCHEMBL2210799

Other measurements 5

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
Sciatic nerveUnclassifiedInhibition— no normalized value— value does not convert to pXRattus norvegicusCHEMBL2210801
Sciatic nerveUnclassifiedInhibition— no normalized value— value does not convert to pXRattus norvegicusCHEMBL2210800
Sciatic nerveUnclassifiedInhibition— no normalized value— value does not convert to pXRattus norvegicusCHEMBL2210798
Sciatic nerveUnclassifiedInhibition— no normalized value— value does not convert to pXRattus norvegicusCHEMBL2210797
Sciatic nerveUnclassifiedInhibition— no normalized value— value does not convert to pXRattus norvegicusCHEMBL2210796