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TargetUnclassified

RAW264.7

Matched no rule. Shown as-is rather than assigned a class by guesswork. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
8
Compounds
5
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

No single gene answers to RAW264.7. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.

Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 3

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
RAW264.7UnclassifiedIC50— no normalized value— value does not convert to pXMus musculusCHEMBL3584412
RAW264.7UnclassifiedIC50— no normalized value— value does not convert to pXMus musculusCHEMBL4338175
RAW264.7UnclassifiedIC50— no normalized value— value does not convert to pXMus musculusCHEMBL4338175

Other measurements 5

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
RAW264.7UnclassifiedActivity— no normalized value— value does not convert to pXMus musculusCHEMBL4338176
RAW264.7UnclassifiedActivity— no normalized value— value does not convert to pXMus musculusCHEMBL4338176
RAW264.7UnclassifiedSurvival— no normalized value— value does not convert to pXMus musculusCHEMBL3381332
RAW264.7UnclassifiedActivity— no normalized value— value does not convert to pXMus musculusCHEMBL858916
RAW264.7UnclassifiedActivity— no normalized value— value does not convert to pXMus musculusCHEMBL858918