TargetOrganisms

Plasmodium falciparum

Whole-organism screens (antiparasitic, antibacterial, antiviral). Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements: 78
Compounds: 32
Binding constants: 0
Median pX: —

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

No single gene answers to Plasmodium falciparum. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.

Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 72

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

Target	Class	Type	Value (nM)	pX	Organism	Assay
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267245
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267245
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267246
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267246
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267247
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267247
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267249
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267249
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267250
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267250
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267251
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1267251
Plasmodium falciparum	Organisms	EC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL761156
Plasmodium falciparum	Organisms	EC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL761156
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1112872
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1112873
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1112874
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL4379992
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL4379993
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL4829240
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL4829241
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5114970
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5114971
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5368271
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5368272
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5551418
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5551419
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794345
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1068610
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1069286
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1614221
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5054966
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5054966
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5054967
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5054967
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794580
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794580
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794580
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794580
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794580
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794580
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794580
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794580
Plasmodium falciparum	Organisms	Potency	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1794580
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1217000
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1217000
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1217000
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1217000
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5114972
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5114973
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL2092593
Plasmodium falciparum	Organisms	IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL2092594

Show all 72 rowsShow first 20

Other measurements 6

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

Target	Class	Type	Value (nM)	pX	Organism	Assay
Plasmodium falciparum	Organisms	Activity	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL1112870
Plasmodium falciparum	Organisms	Ratio IC50	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL5551422
Plasmodium falciparum	Organisms	Activity	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL989405
Plasmodium falciparum	Organisms	Activity	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL989406
Plasmodium falciparum	Organisms	Activity	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL3242008
Plasmodium falciparum	Organisms	Activity	— no normalized value	— value does not convert to pX	Plasmodium falciparum	CHEMBL3242010

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