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PsychedeliaDokholyan Laboratory
TargetCell lines

PC-3

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
42
Compounds
10
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

PC-3 is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 13

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321396
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321396
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321396
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321396
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321396
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321396
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4343249
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5519313
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4033875
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4033875
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4033875
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372549
PC-3Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372552

Other measurements 29

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321403
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321403
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321403
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321403
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321403
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321403
PC-3Cell linesGI50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1963885
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372555
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372556
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372558
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372560
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372562
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372564
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372567
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372568
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372570
PC-3Cell linesInhibition— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372571
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372576
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372577
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372578
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372579
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372583
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372584
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372586
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372588
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372600
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372601
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372602
PC-3Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372603
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