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TargetOrganisms

Oryctolagus cuniculus

Whole-organism screens (antiparasitic, antibacterial, antiviral). Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
44
Compounds
25
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

No single gene answers to Oryctolagus cuniculus. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.

Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 2

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
Oryctolagus cuniculusOrganismsIC50— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771610
Oryctolagus cuniculusOrganismsIC50— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL772346

Other measurements 42

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771878
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771865
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771872
Oryctolagus cuniculusOrganismsKb— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL768053
Oryctolagus cuniculusOrganismsInhibition— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL770380
Oryctolagus cuniculusOrganismsInhibition— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL772595
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL772834
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL772834
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL772834
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL772835
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL767604
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL767611
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771695
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771863
Oryctolagus cuniculusOrganismsActivity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL4388778
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsRelative activity— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773948
Oryctolagus cuniculusOrganismsFC— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL3258832
Oryctolagus cuniculusOrganismsFC— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL3258832
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL767606
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL767606
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL772838
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL767608
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771877
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771870
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771867
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771873
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771864
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL771866
Oryctolagus cuniculusOrganismsNo. of rabbits convulsed— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL772833
Oryctolagus cuniculusOrganismsMin effective dose— no normalized value— value does not convert to pXOryctolagus cuniculusCHEMBL773369