mGluR5
Matched no rule. Shown as-is rather than assigned a class by guesswork. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.
- Measurements
- 3
- Compounds
- 1
- Binding constants
- 3
- Median pX
- 5.70
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
mGluR5 has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.
Resolver said synonym match with no family rule to check it against — recorded by tools/fetch_expression.py, not written here.
III · Ranking
Compounds by strongest binding constant
One bar per compound: its strongest Ki or Kd at this target, expressed as pX. Compounds measured here only by a functional assay do not appear — they are in the table below.
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Equilibrium binding constants 3
Ki and Kd — a concentration at equilibrium. Directly comparable across rows at the same target.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| mGluR5 | Unclassified | Ki | 1,900 | 5.72 | HUMAN | PMID 11080213 |
| mGluR5 | Unclassified | Ki | 2,000 | 5.70 | HUMAN | PMID 9131252 |
| mGluR5 | Unclassified | Ki | 2,870 | 5.54 | PORCINE | PMID 7751958 |