Methyl-CpG-binding domain protein 4
Matched no rule. Shown as-is rather than assigned a class by guesswork. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.
- Measurements
- 2
- Compounds
- 2
- Binding constants
- 0
- Median pX
- —
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
Methyl-CpG-binding domain protein 4
Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein
Quoted from UniProt’s FUNCTION annotation for O95243 (reviewed).
What it acts with
STRING’s highest-confidence human functional partners. The combined score mixes several kinds of evidence, so each channel is shown separately — a partner supported by experiment is a different claim from one supported only by text mining, and for a receptor this is where its coupling appears as evidence rather than as assertion.
Where it sits in the cell
- Nuclear speckles
Human Protein Atlas, by antibody immunofluorescence in cell lines — a different assay from the expression figures below, which are RNA.
UniProt, curated Nucleus
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Other measurements 2
Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| Methyl-CpG-binding domain protein 4 | Unclassified | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL5665444 |
| Methyl-CpG-binding domain protein 4 | Unclassified | Inhibition | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL5665444 |