MDA-MB-231
Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.
- Measurements
- 13
- Compounds
- 6
- Binding constants
- 0
- Median pX
- —
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
MDA-MB-231 is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.
Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Functional readouts 11
IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL1932305 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL2025701 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL2061533 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL3999708 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4817209 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL5519309 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL3419046 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4135697 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4821309 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL5227179 |
| MDA-MB-231 | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL6073991 |
Other measurements 2
Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| MDA-MB-231 | Cell lines | GI50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL1964063 |
| MDA-MB-231 | Cell lines | MIC | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL5245486 |