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PsychedeliaDokholyan Laboratory
TargetCell lines

MCF7

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
56
Compounds
14
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

MCF7 is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 23

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321395
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321395
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321395
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321395
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321395
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321395
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4141852
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3363135
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL963213
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3803069
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3803069
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3803069
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4343242
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4427096
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4817208
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5147085
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5519308
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5551413
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4135698
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL2321033
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4254168
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073990
MCF7Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073914

Other measurements 33

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321402
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321402
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321402
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321402
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321402
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321402
MCF7Cell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL708188
MCF7Cell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL708188
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5519322
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5519323
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5519324
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5519325
MCF7Cell linesGI50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1963882
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6109695
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4200141
MCF7Cell linesInhibition— no normalized value— value does not convert to pXHomo sapiensCHEMBL3363136
MCF7Cell linesInhibition— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073912
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073926
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073927
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073928
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073929
MCF7Cell linesInhibition— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073930
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073933
MCF7Cell linesFC— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073936
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073943
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073944
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073945
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073949
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073955
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073956
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073957
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073958
MCF7Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073959
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