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TargetOrganisms

Leishmania infantum

Whole-organism screens (antiparasitic, antibacterial, antiviral). Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
16
Compounds
8
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

No single gene answers to Leishmania infantum. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.

Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 16

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL3367768
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL3367768
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL3367768
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL3367769
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL3367769
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL3367769
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL4718648
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL4718648
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL4718648
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL945385
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL1217010
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL1217010
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL1217010
Leishmania infantumOrganismsIC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL1217010
Leishmania infantumOrganismsEC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL3381330
Leishmania infantumOrganismsEC50— no normalized value— value does not convert to pXLeishmania infantumCHEMBL3381331