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PsychedeliaDokholyan Laboratory
TargetCell lines

KB

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
17
Compounds
6
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

KB is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 8

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
KBCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL835249
KBCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL835249
KBCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL834815
KBCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL834815
KBCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL2319534
KBCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL2321022
KBCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3390169
KBCell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5320616

Other measurements 9

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
KBCell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1020079
KBCell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL703151
KBCell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL703151
KBCell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL699914
KBCell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL703346
KBCell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL703346
KBCell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL703340
KBCell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL703340
KBCell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL699913
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