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TargetUnclassified

Ileum

Matched no rule. Shown as-is rather than assigned a class by guesswork. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
9
Compounds
3
Binding constants
2
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

No single gene answers to Ileum. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.

Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Equilibrium binding constants 2

Ki and Kd — a concentration at equilibrium. Directly comparable across rows at the same target.

TargetClassTypeValue (nM)pXOrganismAssay
IleumUnclassifiedKd— no normalized value— value does not convert to pXCavia porcellusCHEMBL3069350
IleumUnclassifiedKd— no normalized value— value does not convert to pXCavia porcellusCHEMBL966036

Functional readouts 1

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
IleumUnclassifiedIC50— no normalized value— value does not convert to pXCavia porcellusCHEMBL967317

Other measurements 6

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
IleumUnclassifiedActivity— no normalized value— value does not convert to pXCavia porcellusCHEMBL1017375
IleumUnclassifiedActivity— no normalized value— value does not convert to pXCavia porcellusCHEMBL1017376
IleumUnclassifiedActivity— no normalized value— value does not convert to pXCavia porcellusCHEMBL1017377
IleumUnclassifiedActivity— no normalized value— value does not convert to pXCavia porcellusCHEMBL1017377
IleumUnclassifiedInhibition— no normalized value— value does not convert to pXRattus norvegicusCHEMBL3767679
IleumUnclassifiedINH— no normalized value— value does not convert to pXCavia porcellusCHEMBL3069351