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PsychedeliaDokholyan Laboratory
TargetCell lines

HT-29

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
17
Compounds
5
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

HT-29 is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 5

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
HT-29Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4343248
HT-29Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626417
HT-29Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5519311
HT-29Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5614548
HT-29Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL2321028

Other measurements 12

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
HT-29Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626446
HT-29Cell linesGI50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1964006
HT-29Cell linesGI50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1964006
HT-29Cell linesGI50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1964006
HT-29Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626455
HT-29Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626457
HT-29Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626458
HT-29Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626461
HT-29Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626465
HT-29Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626466
HT-29Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626467
HT-29Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4200143
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