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PsychedeliaDokholyan Laboratory
TargetCell lines

HepG2

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
36
Compounds
13
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

HepG2 is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 25

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321397
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321397
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321397
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321397
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321397
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321397
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4377240
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL963212
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL2321034
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4254167
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4262063
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4341187
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4379995
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4626418
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4829243
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5114977
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5147082
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5368274
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5519310
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5551411
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5614481
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL963121
HepG2Cell linesPotency— no normalized value— value does not convert to pXHomo sapiensCHEMBL1794553
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6109686
HepG2Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL2092591

Other measurements 11

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321404
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321404
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321404
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321404
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321404
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321404
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5255814
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4200142
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL3606735
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL3606944
HepG2Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4832634
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