HeLa
Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.
- Measurements
- 12
- Compounds
- 6
- Binding constants
- 0
- Median pX
- —
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
HeLa is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.
Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Functional readouts 11
IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| HeLa | Cell lines | EC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4629657 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL963209 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL2321037 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL3803065 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL3803065 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL3803065 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4141851 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4263656 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4386667 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL963118 |
| HeLa | Cell lines | IC50 | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL6109685 |
Other measurements 1
Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| HeLa | Cell lines | Activity | — no normalized value | — value does not convert to pX | Homo sapiens | CHEMBL4200144 |