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PsychedeliaDokholyan Laboratory
TargetCell lines

HEK293

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
34
Compounds
13
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

HEK293 is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 32

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
HEK293Cell linesPotency— no normalized value— value does not convert to pXHomo sapiensCHEMBL1794308
HEK293Cell linesPotency— no normalized value— value does not convert to pXHomo sapiensCHEMBL1794308
HEK293Cell linesPotency— no normalized value— value does not convert to pXHomo sapiensCHEMBL1794308
HEK293Cell linesPotency— no normalized value— value does not convert to pXHomo sapiensCHEMBL1794308
HEK293Cell linesPotency— no normalized value— value does not convert to pXHomo sapiensCHEMBL1794308
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1113947
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1113947
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1113947
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1113947
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169105
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169105
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169105
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169106
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169106
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169106
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169107
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169107
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169107
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169108
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169108
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1169108
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1676764
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1676764
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1676764
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1676763
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1676763
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1676763
HEK293Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3611198
HEK293Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3611198
HEK293Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6117186
HEK293Cell linesEC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5531589
HEK293Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073915

Other measurements 2

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
HEK293Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL6117184
HEK293Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL1116561
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