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PsychedeliaDokholyan Laboratory
TargetCell lines

DU-145

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
25
Compounds
3
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

DU-145 is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 6

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
DU-145Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4141850
DU-145Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4386668
DU-145Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073996
DU-145Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5245481
DU-145Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372548
DU-145Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372551

Other measurements 19

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
DU-145Cell linesGI50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1964017
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372554
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372557
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372559
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372561
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372563
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372565
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372566
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372569
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372572
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372573
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372574
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372575
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372580
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372581
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372582
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372585
DU-145Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372587
DU-145Cell linesInhibition— no normalized value— value does not convert to pXHomo sapiensCHEMBL5372599
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