BV-2
Matched no rule. Shown as-is rather than assigned a class by guesswork. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.
- Measurements
- 14
- Compounds
- 4
- Binding constants
- 0
- Median pX
- —
I · Identity
What this target is
Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.
No single gene answers to BV-2. Names like this one are families or unsubtyped preparations — a measurement made against whatever receptors a tissue carried, before or without resolving which subtype bound the compound. A family has no one accession, and picking a member to stand for it would invent a precision the assay never had: asked for “Muscarinic acetylcholine receptor” UniProt returns CHRM1, and that answer is wrong.
Resolver said no gene lists this target name as a synonym — recorded by tools/fetch_expression.py, not written here.
IV · Evidence
Every measurement at this target
Each row links to the ChEMBL assay it came from.
Functional readouts 6
IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| BV-2 | Unclassified | IC50 | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL4821665 |
| BV-2 | Unclassified | IC50 | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL4821666 |
| BV-2 | Unclassified | IC50 | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5364302 |
| BV-2 | Unclassified | IC50 | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5364302 |
| BV-2 | Unclassified | IC50 | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5364303 |
| BV-2 | Unclassified | IC50 | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5364303 |
Other measurements 8
Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.
| Target | Class | Type | Value (nM) | pX | Organism | Assay |
|---|---|---|---|---|---|---|
| BV-2 | Unclassified | Activity | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5624325 |
| BV-2 | Unclassified | Inhibition | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL4821667 |
| BV-2 | Unclassified | Activity | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL4821668 |
| BV-2 | Unclassified | Activity | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5364308 |
| BV-2 | Unclassified | Activity | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5364309 |
| BV-2 | Unclassified | Activity | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5364310 |
| BV-2 | Unclassified | Activity | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5225197 |
| BV-2 | Unclassified | Activity | — no normalized value | — value does not convert to pX | Mus musculus | CHEMBL5225198 |