TargetTissue and matrix

Brain

Preparations such as liver microsomes or whole blood. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements: 20
Compounds: 2
Binding constants: 0
Median pX: —

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

Brain has no protein record here. A name resolves when ChEMBL’s own target record gives an accession, when the name appears verbatim in a gene’s synonym list, or when it matches a UniProt protein name exactly. Guessing from a name that merely looks like a receptor is how a histone gene ends up filed as an adrenoceptor.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Other measurements 20

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

Target	Class	Type	Value (nM)	pX	Organism	Assay
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Macaca fascicularis	CHEMBL3537181
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Macaca fascicularis	CHEMBL3537181
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Canis lupus familiaris	CHEMBL3537180
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Canis lupus familiaris	CHEMBL3537180
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Mus musculus	CHEMBL3537178
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Mus musculus	CHEMBL3537178
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Rattus norvegicus	CHEMBL3537177
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Rattus norvegicus	CHEMBL3537177
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Rattus norvegicus	CHEMBL3537176
Brain	Tissue and matrix	Fu	— no normalized value	— value does not convert to pX	Rattus norvegicus	CHEMBL3537176
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Mus musculus	CHEMBL1071191
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Rattus norvegicus	CHEMBL901028
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Mus musculus	CHEMBL1020759
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Rattus norvegicus	CHEMBL954090
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Mus musculus	CHEMBL1071193
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Rattus norvegicus	CHEMBL1022922
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Rattus norvegicus	CHEMBL1022921
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Mus musculus	CHEMBL1071195
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Mus musculus	CHEMBL1071189
Brain	Tissue and matrix	Drug uptake	— no normalized value	— value does not convert to pX	Mus musculus	CHEMBL2156605

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