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PsychedeliaDokholyan Laboratory
TargetCell lines

A549

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
34
Compounds
14
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

A549 is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 19

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321394
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321394
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321394
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321394
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321394
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321394
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3803068
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3803068
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL3803068
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4141849
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4386669
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4427099
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL4810910
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5147086
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5519312
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL5614480
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6109688
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL2321031
A549Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6073981

Other measurements 15

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
A549Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321401
A549Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321401
A549Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321401
A549Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321401
A549Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321401
A549Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4321401
A549Cell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL621413
A549Cell linesED50— no normalized value— value does not convert to pXHomo sapiensCHEMBL621413
A549Cell linesGI50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1963854
A549Cell linesGI50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1963854
A549Cell linesGI50— no normalized value— value does not convert to pXHomo sapiensCHEMBL1963854
A549Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5255813
A549Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL4810913
A549Cell linesCC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6116982
A549Cell linesCC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL6116985
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