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PsychedeliaDokholyan Laboratory
TargetCell lines

A2780

Phenotypic screens. A value here is a cellular response, not a binding affinity. Values below are reported as measured; because this is not a molecular target, they are not treated as affinities anywhere on this site.

Measurements
27
Compounds
6
Binding constants
0
Median pX
—

I · Identity

What this target is

Its function as UniProt states it, where in a cell the protein is found, and which cell types and tissues transcribe its gene.

A2780 is a cell line or an assay label, not a protein, so there is no gene to describe. Its measurements are still shown below — they are real, and they are measurements of what a compound did in that system rather than of what it binds.

Resolver said a cell line or assay label, not a gene — recorded by tools/fetch_expression.py, not written here.

IV · Evidence

Every measurement at this target

Each row links to the ChEMBL assay it came from.

Functional readouts 4

IC₅₀, EC₅₀, AC₅₀ and potency. Assay-dependent, and not interchangeable with a binding constant.

TargetClassTypeValue (nM)pXOrganismAssay
A2780Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL991218
A2780Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL991218
A2780Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL991218
A2780Cell linesIC50— no normalized value— value does not convert to pXHomo sapiensCHEMBL991218

Other measurements 23

Everything else ChEMBL recorded for this compound — percentage inhibition, efficacy, half-life, cytotoxicity. Reported in the assay's own units, which is why no value is converted here.

TargetClassTypeValue (nM)pXOrganismAssay
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535370
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535371
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535372
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535375
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535377
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535379
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535380
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535381
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535385
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535386
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535387
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535405
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535406
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535407
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535410
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535411
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535412
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535413
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535414
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535415
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535416
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL5535417
A2780Cell linesActivity— no normalized value— value does not convert to pXHomo sapiensCHEMBL999935
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